作者
Isela Esther Juárez-Rojop, Juan C Díaz-Zagoya, Jorge L Ble-Castillo, Pedro H Miranda-Osorio, Andrés E Castell-Rodríguez, Carlos A Tovilla-Zárate, Arturo Rodríguez-Hernández, Hidemi Aguilar-Mariscal, Teresa Ramón-Frías, Deysi Y Bermúdez-Ocaña
发表日期
2012/12
期刊
BMC complementary and alternative medicine
卷号
12
页码范围
1-11
出版商
BioMed Central
简介
Background
Traditional plant treatment for diabetes has shown a surging interest in the last few decades. Therefore, the purpose of this study was to assess the hypoglycemic effect of the aqueous extract of C. papaya leaves in diabetic rats. Several studies have reported that some parts of the C. papaya plant exert hypoglycemic effects in both animals and humans.
Methods
Diabetes was induced in rats by intraperitoneal administration of 60 mg/kg of streptozotocin (STZ). The aqueous extract of C. papaya was administered in three different doses (0.75, 1.5 and 3 g/100 mL) as drinking water to both diabetic and non-diabetic animals during 4 weeks.
Results
The aqueous extract of Carica papaya (0.75 g and 1.5 g/100 mL) significantly decreased blood glucose levels (p<0.05) in diabetic rats. It also decreased cholesterol …
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IE Juárez-Rojop, JC Díaz-Zagoya, JL Ble-Castillo… - BMC complementary and alternative medicine, 2012