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Exploring possible relationships among forgiveness, disease, and physical health is truly at the frontiers of forgiveness research. To date, no controlled studies have demonstrated that forgiveness affects physical health outcomes either positively or negatively. This chapter elaborates on why people are encouraged to pursue research on health and forgiveness, discusses conceptual frameworks that are potentially useful in understanding the possible link between forgiveness and physical health, and considers some conceptual and methodological issues. The authors first comment briefly on the term" forgiveness" as used in this chapter.(PsycInfo Database Record (c) 2023 APA, all rights reserved)