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PURPOSE: Current guidelines for the readiness for Spontaneous Breathing Trials (SBT) and the ability to be weaned off a ventilator includes oxygen saturation (SaO2)≥ 89% on fraction of inspired oxygen (FiO2)≤ 40%. Our study compared outcomes of patients who underwent a tracheostomy at different FiO2 settings with the aim to facilitate optimal settings for a tracheostomy.

METHODS: We performed a retrospective observational cohort study of 604 consecutive tracheostomized patients hospitalized in an intensive care unit (ICU) within the Mount Sinai Health System between March 2020 to September 2021. We analyzed clinical characteristics and outcomes of patients who underwent a tracheostomy at FiO2 settings of≥ 50% or< 50%.

RESULTS: 221 patients were tracheostomized at FiO2≥ 50% and 383 patients were tracheostomized at FiO2< 50%. Both groups had a similar mean age (61.94 and 61.83 years …