作者
Babak Karimi, Hassan Seradj
发表日期
2000
期刊
Synlett
卷号
2000
期号
06
页码范围
0805-0806
出版商
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
简介
Different types of aldehydes and ketones can be efficiently converted into their corresponding 1, 3-oxathiolanes using 2-mercaptoethanol (1.5-3.2 equiv.) in the presence of catalytic amount (0.04-0.15 equiv.) of ZrCl4 in CH2Cl2 as solvent at room temperature. Chemoselective monothioacetalization of aldehydes in the presence of ketones can also be achieved in high yield. The work-up is easy and removal of water is not necessary.
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