作者
Maria J Wawer, Aaron AR Tobian, Godfrey Kigozi, Xiangrong Kong, Patti E Gravitt, David Serwadda, Fred Nalugoda, Frederick Makumbi, Victor Ssempiija, Nelson Sewankambo, Stephen Watya, Kevin P Eaton, Amy E Oliver, Michael Z Chen, Steven J Reynolds, Thomas C Quinn, Ronald H Gray
发表日期
2011/1/15
期刊
The Lancet
卷号
377
期号
9761
页码范围
209-218
出版商
Elsevier
简介
Background
Randomised trials show that male circumcision reduces the prevalence and incidence of high-risk human papillomavirus (HPV) infection in men. We assessed the efficacy of male circumcision to reduce prevalence and incidence of high-risk HPV in female partners of circumcised men.
Methods
In two parallel but independent randomised controlled trials of male circumcision, we enrolled HIV-negative men and their female partners between 2003 and 2006, in Rakai, Uganda. With a computer-generated random number sequence in blocks of 20, men were assigned to undergo circumcision immediately (intervention) or after 24 months (control). HIV-uninfected female partners (648 of men from the intervention group, and 597 of men in the control group) were simultaneously enrolled and provided interview information and self-collected vaginal swabs at baseline, 12 months, and 24 months. Vaginal swabs …
学术搜索中的文章
MJ Wawer, AAR Tobian, G Kigozi, X Kong, PE Gravitt… - The Lancet, 2011