作者
Carolyn B Coulam, Mahmood Bilal, Maria D Salazar Garcia, Dimantha Katukurundage, Haidy Elazzamy, Emilio F Fernandez, Joanne Kwak‐Kim, Kenneth Beaman, Svetlana V Dambaeva
发表日期
2018/7
期刊
American Journal of Reproductive Immunology
卷号
80
期号
1
页码范围
e12862
简介
Problem
To study the prevalence of HHV‐6 in endometrial biopsies among women experiencing recurrent implantation failure (RIF) after IVF/ET compared with controls.
Method of Study
Thirty women experiencing RIF after IVF/ET and 10 fertile women participated in the study. All women had endometrial biopsies taken in the luteal phase of their menstrual cycle for an endometrial immune profile (EIP) and HHV‐6 mRNA as well as lymphocyte and granulocyte populations. The prevalence of HHV‐6 in endometrial biopsies was determined, and biopsies for positive and negative expression of HHV‐6 were compared with the results of their EIP and lymphocyte and granulocyte populations.
Results
Thirty‐seven percentage of women with a history of RIF and 0% of controls demonstrated the presence of HHV‐6 in their endometrial biopsies. No associations were found when the results of the endometrial immune …
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CB Coulam, M Bilal, MD Salazar Garcia… - American Journal of Reproductive Immunology, 2018