作者
Ming-Hui Chen, Joseph G Ibrahim, Debajyoti Sinha
发表日期
2002/1/1
期刊
Journal of Multivariate Analysis
卷号
80
期号
1
页码范围
101-126
出版商
Academic Press
简介
We develop Bayesian methods for right censored multivariate failure time data for populations with a cure fraction. We propose a new model, called the multivariate cure rate model, and provide a natural motivation and interpretation of it. To create the correlation structure between the failure times, we introduce a frailty term, which is assumed to have a positive stable distribution. The resulting correlation structure induced by the frailty term is quite appealing and leads to a nice characterization of the association between the failure times. Several novel properties of the model are derived. First, conditional on the frailty term, it is shown that the model has a proportional hazards structure with the covariates depending naturally on the cure rate. Second, we establish mathematical relationships between the marginal survivor functions of the multivariate cure rate model and the more standard mixture model for modelling …
引用总数
20012002200320042005200620072008200920102011201220132014201520162017201820192020202120222023202411314478512787849910274622
学术搜索中的文章