作者
Satoshi Takeuchi, Eric M Rohren, Reham Abdel-Wahab, Lianchun Xiao, Jeffrey S Morris, Homer A Macapinlac, Manal M Hassan, Ahmed O Kaseb
发表日期
2017/6
期刊
European journal of nuclear medicine and molecular imaging
卷号
44
页码范围
969-978
出版商
Springer Berlin Heidelberg
简介
Purpose
18F-fluorodeoxyglucose positron emission tomopraphy/computed tomography (FDGPET/CT) has been proven to be useful for imaging many types of cancer; however, its role is not well defined in hepatocellular carcinoma (HCC). We assessed the prognostic value of metabolic imaging biomarkers as established by baseline pretreatment FDG PET/CT in patients with HCC.
Methods
We retrospectively analyzed the records of patients with HCC who underwent FDG PET/CT before initial treatment from May 2013 through May 2014. Four PET/CT parameters were measured: maximum standardized uptake value (SUVmax), total lesion glycolysis (TLG), metabolic tumor volume (MTV), and tumor-to-normal-liver SUV ratio (TNR). Optimal cut-off values for the PET/CT parameters to stratify patients in terms of overall survival (OS) were …
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S Takeuchi, EM Rohren, R Abdel-Wahab, L Xiao… - European journal of nuclear medicine and molecular …, 2017