作者
Monica S Cooper, Melinda Randall, Margaret Rowell, Margaret Charlton, Anthea Greenway, Chris Barnes
发表日期
2016/3
期刊
Pediatric Blood & Cancer
卷号
63
期号
3
页码范围
558-560
简介
We report a case of prophylactic management with methylene blue (MB) in an almost 4‐year‐old male with congenital methemoglobinemia type II. He has a CYB5R3 compound heterozygote mutation, causing a cytochrome‐b(5) reductase deficiency. Since the MB treatment regimen has commenced, his methemoglobin level has been significantly lower. He has shown modest behavioral improvements (as assessed on the Achenbach behavior report scales). There have been no iatrogenic side effects. These findings are encouraging for symptomatic improvement with regular prophylactic MB treatment but represent a single case report, which must be interpreted with caution.
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MS Cooper, M Randall, M Rowell, M Charlton… - Pediatric Blood & Cancer, 2016