作者
Rakel Olinda Macedo da Silva, José Walber Gonçalves Castro, Orlando de Menezes Dantas Junior, Ana Carolina Justino de Araújo, Maria Karollyna do Nascimento Silva Leandro, Raíra Justino Oliveira Costa, Luciely Leite Pinto, Lívia Maria Garcia Leandro, Luiz E da Silva, Wanderlei do Amaral, Lucas D Parabocz, Aurea P Ferriani, Bruna Garcia, Beatriz HLN Sales Maia, Janaína Esmeraldo Rocha, Camila Fonseca Bezerra, Thiago Sampaio de Freitas, Maria Socorro Costa, Fábia Ferreira Campina, Edinardo Fagner Ferreira Matias, Marcello Iriti, Henrique Douglas Melo Coutinho
发表日期
2019/12
期刊
Antibiotics
卷号
8
期号
4
出版商
Multidisciplinary Digital Publishing Institute (MDPI)
简介
The objective of this work was to evaluate the phytochemical composition and the antibacterial and antibiotic-modulating activities of the essential oils of Eugenia brasiliensis Lam (OEEb) and Piper mosenii C. DC (OEPm) singly or in association with blue LED (Light-emitting diode) light. The antibacterial and antibiotic-modulatory activities of the essential oils on the activity of aminoglycosides were evaluated to determine the minimum inhibitory concentration (MIC, μg/mL) in the presence or absence of exposure to blue LED light. The chemical analysis showed α-pinene and bicyclogermacrene as major constituents of OEPm, whereas α-muurolol was the main compound of OEEb. Both OEEb and OEPm showed MIC≥ 512 μg/mL against the strains under study. However, the association of these oils with the blue LED light enhanced the action of the aminoglycosides amikacin and gentamicin. In conclusion, the …
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ROM da Silva, JWG Castro, OMD Junior… - Antibiotics, 2019