作者
Raza M Alvi, Markella V Zanni, Anne M Neilan, Malek ZO Hassan, Noor Tariq, Lili Zhang, Maryam Afshar, Dahlia Banerji, Connor P Mulligan, Adam Rokicki, Magid Awadalla, James L Januzzi, Tomas G Neilan
发表日期
2020/8/22
期刊
Clinical Infectious Diseases
卷号
71
期号
5
页码范围
1306-1315
出版商
Oxford University Press
简介
Background
Among persons living with human immunodeficiency virus (PHIV), incident heart failure (HF) rates are increased and outcomes are worse; however, the role of amino-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations among PHIV with HF has not been characterized.
Methods
Patients were derived from a registry of those hospitalized with HF at an academic center in a calender year. We compared the NT-proBNP concentrations and the changes in NT-proBNP levels between PHIV with HF and uninfected controls with HF.
Results
Among 2578 patients with HF, there were 434 PHIV; 90% were prescribed antiretroviral therapy and 62% were virally suppressed. As compared to controls, PHIV had higher admission (3822 [IQR, 2413–7784] pg/ml vs 5546 [IQR, 3257–8792] pg/ml, respectively; P < .001), higher discharge (1922 [IQR …
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RM Alvi, MV Zanni, AM Neilan, MZO Hassan, N Tariq… - Clinical Infectious Diseases, 2020