作者
Raza M Alvi, Anne M Neilan, Noor Tariq, Malek O Hassan, Magid Awadalla, Lili Zhang, Maryam Afshar, Adam Rokicki, Connor P Mulligan, Virginia A Triant, Markella V Zanni, Tomas G Neilan
发表日期
2019/9
期刊
JACC: Heart Failure
卷号
7
期号
9
页码范围
759-767
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to determine the incidence of sudden cardiac death (SCD) among persons living with human immunodeficiency virus infection (PHIV) with heart failure (HF), who were hospitalized for HF, and the risk factors associated with it.
Background
HF is associated with an increased risk for SCD. PHIV are at heightened risk for HF.
Methods
This was a retrospective study of 2,578 patients hospitalized with HF from a single academic center, of whom 344 were PHIV. The outcome of interest was SCD. Subgroup analyses were performed by strata of viral load (VL) and left ventricular ejection fraction (LVEF) <35%, 35% to 49%, and ≥50%.
Results
Of 2,578 patients with HF, 2,149 (86%) did not have implantable cardioverter-defibrillators; of these, there were 344 PHIV and 1,805 uninfected control subjects. Among PHIV with HF, 313 (91%) were prescribed antiretroviral therapy and 64% were …
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RM Alvi, AM Neilan, N Tariq, MO Hassan, M Awadalla… - JACC: Heart Failure, 2019