作者
E Cinotti, B Labeille, S Debarbieux, C Carrera, F Lacarrubba, AM Witkowski, E Moscarella, E Arzberger, H Kittler, P Bahadoran, S Gonzalez, P Guitera, M Agozzino, F Farnetani, R Hofmann‐Wellenhof, M Ardigò, P Rubegni, L Tognetti, Joanna Łudzik, I Zalaudek, G Argenziano, C Longo, S Ribero, J Malvehy, G Pellacani, F Cambazard, JL Perrot
发表日期
2018/8
期刊
Journal of the European Academy of Dermatology and Venereology
卷号
32
期号
8
页码范围
1284-1291
简介
Background
Several dermoscopic and in vivo reflectance confocal microscopy (RCM) diagnostic criteria of lentigo maligna (LM)/lentigo maligna melanoma (LMM) have been identified. However, no study compared the diagnostic accuracy of these techniques.
Objective
We evaluated the diagnostic accuracy of dermoscopy and RCM for LM/LMM using a holistic assessment of the images.
Methods
A total of 223 facial lesions were evaluated by 21 experts. Diagnostic accuracy of the clinical, dermoscopic and RCM examination was compared. Interinvestigator variability and confidence level in the diagnosis were also evaluated.
Results
Overall diagnostic accuracy of the two imaging techniques was good (area under the curve of the sROC function: 0.89). RCM was more sensitive (80%, vs. 61%) and less specific (81% vs. 92%) than dermoscopy for LM/LMM. In particular, RCM showed a higher sensitivity for …
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E Cinotti, B Labeille, S Debarbieux, C Carrera… - Journal of the European Academy of Dermatology and …, 2018