作者
Jonathan M Coutinho, David S Liebeskind, Lee-Anne Slater, Raul G Nogueira, Wayne Clark, Antoni Dávalos, Alain Bonafé, Reza Jahan, Urs Fischer, Jan Gralla, Jeffrey L Saver, Vitor M Pereira
发表日期
2017/3/1
期刊
JAMA neurology
卷号
74
期号
3
页码范围
268-274
出版商
American Medical Association
简介
Importance
Mechanical thrombectomy (MT) improves clinical outcomes in patients with acute ischemic stroke (AIS) caused by a large vessel occlusion. However, it is not known whether intravenous thrombolysis (IVT) is of added benefit in patients undergoing MT.
Objective
To examine whether treatment with IVT before MT with a stent retriever is beneficial in patients undergoing MT.
Design, Setting, and Participants
This post hoc analysis used data from 291 patients treated with MT included in 2 large, multicenter, prospective clinical trials that evaluated MT for AIS (Solitaire With the Intention for Thrombectomy performed from January 1, 2010, through December 31, 2011, and Solitaire Flow Restoration Thrombectomy for Acute Revascularization from January 1, 2010, through December 31, 2012). An independent core laboratory scored the radiologic outcomes in each trial.
Interventions
Patients were treated with IVT …
学术搜索中的文章
JM Coutinho, DS Liebeskind, LA Slater, RG Nogueira… - JAMA neurology, 2017