作者
Biljana Marjanovic-Painter, Janke Kleynhans, Jan Rijn Zeevaart, Egmont Rohwer, Thomas Ebenhan
发表日期
2023/1/1
来源
Nuclear Medicine and Biology
卷号
116
页码范围
108307
出版商
Elsevier
简介
Background
Ubiquicidin is a peptide fragment with selective binding to negatively charged bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it has been labelled with Positron Emission Tomography (PET) radionuclides in the last decade for imaging infection and distinguishing infectious disease from sterile inflammation. This systematic review aims to evaluate the technology readiness level of PET based ubiquicidin radiopharmaceuticals.
Methods
Two independent researchers reviewed all articles and abstracts pertaining ubiquicidin and PET imaging that are currently available. Scopus, Google Scholar and PubMed/Medline were used in the search. Upon completion of the literature search all articles and abstracts were evaluated and duplicates were excluded. All non-PET articles as well as review articles without new data were deemed ineligible.
Results
From a total of 17 …
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