作者
Sondas Alsharidah, Mariam Ayed, Reem M Ameen, Fatma Alhuraish, Najat A Rouheldeen, Farah R Alshammari, Alia Embaireeg, Mariam Almelahi, Maitham Adel, Mohammed E Dawoud, Mohammad A Aljasmi, Nashmi Alshammari, Abdullah Alsaeedi, Wasel Al-Adsani, Hussan Arian, Husain Awad, Humoud A Alenezi, Azeez Alzafiri, Enas F Gouda, Mohammad Almehanna, Salem Alqahtani, Abdulrahman Alshammari, Medhat Z Askar
发表日期
2021/2/1
期刊
International Journal of Infectious Diseases
卷号
103
页码范围
439-446
出版商
Elsevier
简介
Objective
To study the effectiveness of COVID-19 convalescent plasma (CCP) therapy for patients with moderate and severe COVID-19 disease.
Methods
This non-randomized prospective cohort study was conducted from May 21 to June 30, 2020, at four major tertiary hospitals in Kuwait. CCP was administered to 135 patients. The control group comprised 233 patients who received standard treatment. All patients (N = 368, median age 54 [range 15–82]) had laboratory-confirmed SARS-CoV-2 infection and either moderate or severe COVID-19 disease.
Results
CCP treatment was associated with a higher rate of clinical improvement in patients with moderate or severe disease. Among those with moderate COVID-19 disease, time to clinical improvement was 7 days in the CCP group, versus 8 days in the control group (p = 0·006). For severe COVID-19 disease, time to clinical improvement was 7 days in the CCP …
学术搜索中的文章
S Alsharidah, M Ayed, RM Ameen, F Alhuraish… - International Journal of Infectious Diseases, 2021
