作者
James B Galloway, Sam Norton, Richard D Barker, Andrew Brookes, Ivana Carey, Benjamin D Clarke, Raeesa Jina, Carole Reid, Mark D Russell, Ruth Sneep, Leah Sugarman, Sarah Williams, Mark Yates, James Teo, Ajay M Shah, Fleur Cantle
发表日期
2020/8/1
期刊
Journal of Infection
卷号
81
期号
2
页码范围
282-288
出版商
WB Saunders
简介
Background
The COVID-19 pandemic continues to escalate. There is urgent need to stratify patients. Understanding risk of deterioration will assist in admission and discharge decisions, and help selection for clinical studies to indicate where risk of therapy-related complications is justified.
Methods
An observational cohort of patients acutely admitted to two London hospitals with COVID-19 and positive SARS-CoV-2 swab results was assessed. Demographic details, clinical data, comorbidities, blood parameters and chest radiograph severity scores were collected from electronic health records. Endpoints assessed were critical care admission and death. A risk score was developed to predict outcomes.
Findings
Analyses included 1,157 patients. Older age, male sex, comorbidities, respiratory rate, oxygenation, radiographic severity, higher neutrophils, higher CRP and lower albumin at presentation predicted critical …
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JB Galloway, S Norton, RD Barker, A Brookes, I Carey… - Journal of Infection, 2020