作者
Pedro A Valdes-Hernandez, Soamy Montesino-Goicolea, Lorraine Hoyos, Eric C Porges, Zhiguang Huo, Natalie C Ebner, Adam J Woods, Ronald Cohen, Joseph L Riley III, Roger B Fillingim, Yenisel Cruz-Almeida
发表日期
2021/12/1
期刊
Pain Reports
卷号
6
期号
4
页码范围
e978
出版商
LWW
简介
Objectives:
This cross-sectional study aimed at determining how worst musculoskeletal pain intensity (WPINT) moderated the association between worst musculoskeletal pain duration (WPDUR) and brain resting-state magnetic resonance imaging functional connectivity (RSFC) in community-dwelling older adults (60–94 years, 75% females, 97% right-handed).
Methods:
Resting-state magnetic resonance imaging functional connectivity between region of interests was linearly regressed on WPDUR and WPINT. Predictions were compared with a control group's average RSFC (61–85 years, 47% females, 95% right-handed).
Results:
Three significant patterns emerged:(1) the positive association between WPDUR and RSFC between the medial prefrontal cortex, in the anterior salience network (SN), and bilateral lateral Brodmann area 6, in the visuospatial network (VSN), in participants with more severe chronic pain …
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