作者
Noorollah Tahery, Mahmood Khodadost, Somayeh Jahani Sherafat, Mostafa Rezaei Tavirani, Nayebali Ahmadi, Fatemeh Montazer, Majid Rezaei Tavirani, Nosratollah Naderi
发表日期
2021
期刊
Gastroenterology and hepatology from bed to bench
卷号
14
期号
Suppl1
页码范围
S118
出版商
Shahid Beheshti University of Medical Sciences
简介
Aim:
The present study aimed to introduce a possible biomarker to differentiate between severe and fatal conditions of COVID-19.
Background:
The COVID-19 pandemic, appearing as a complicated health problem, has changed the lifestyle of people in recent years. Clinical findings indicate mild, severe, and fatal conditions of this disease. Prediction of disease severity is a significant point in managing COVID-19 infection
Methods:
In this study, 195 differentially expressed genes (DEGs) that discriminate between fatal and severe conditions in patients were extracted from the literature and screened to determine the significant ones. The significant DEGs plus the 90 first neighbors added from the STRING database were included in the interactome using Cytoscape software v 3.7. 2. The central nodes of the analyzed network were identified and assessed.
Results:
Ten significant DEGs were candidates for assessment, of …
学术搜索中的文章
N Tahery, M Khodadost, SJ Sherafat, MR Tavirani… - Gastroenterology and hepatology from bed to bench, 2021