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The aim of this study was to assess the effects of the variables related to family functioning (parental monitoring, family support, and family conflict) on juvenile antisocial behavior either directly or indirectly through the choice of deviant friends. Thus, the sample consisted of 764 adolescents from the Autonomous Community of Galicia (Spain), from juvenile offender centres (mean age = 17.12, 87.4% males) and students from local schools (mean age = 16.06, 45.5% males). The scales of Valoración del Riesgo en Adolescentes Infractores [Juvenile Offenders Risk Assessment] on parental monitoring, family conflict, family support, antisocial peer group, and antisocial behavior, were applied. The results of structural equation modelling showed a better fit of the mediation model. The results are discussed in terms of their implications for the prevention, risk assessment, and management of juvenile offenders.