作者
Rui Ding, Yong He, Xiao Wang, Jingli Xu, Yurong Chen, Man Feng, Chuanmin Qi
发表日期
2011/7/1
期刊
Molecules
卷号
16
期号
7
页码范围
5665-5673
出版商
Molecular Diversity Preservation International
简介
Treatment of substituted benzyl alcohols with tosyl chloride resulted in the formation of the corresponding chlorides, not the usual tosylates. A series of experiments demonstrated that it was possible to predict whether chlorination or tosylation would occur for substituted benzyl alcohols and pyridine methanols. Treatment of electron withdrawing group-substituted benzyl alcohols with tosyl chloride gave the corresponding chlorides in moderate yields under mild conditions, which provided a simple way to directly prepare chlorides from alcohols.
学术搜索中的文章
R Ding, Y He, X Wang, J Xu, Y Chen, M Feng, C Qi - Molecules, 2011