作者
Brenda WJH Penninx, Willem A Nolen, Femke Lamers, Frans G Zitman, Johannes H Smit, Philip Spinhoven, Pim Cuijpers, Peter J de Jong, Harm WJ van Marwijk, Klaas van der Meer, Peter Verhaak, Miranda GH Laurant, Ron de Graaf, Witte J Hoogendijk, Nic van der Wee, Johan Ormel, Richard van Dyck, Aartjan TF Beekman
发表日期
2011/9/1
期刊
Journal of affective disorders
卷号
133
期号
1-2
页码范围
76-85
出版商
Elsevier
简介
BACKGROUND
Whether course trajectories of depressive and anxiety disorders are different, remains an important question for clinical practice and informs future psychiatric nosology. This longitudinal study compares depressive and anxiety disorders in terms of diagnostic and symptom course trajectories, and examines clinical prognostic factors.
METHODS
Data are from 1209 depressive and/or anxiety patients residing in primary and specialized care settings, participating in the Netherlands Study of Depression and Anxiety. Diagnostic and Life Chart Interviews provided 2-year course information.
RESULTS
Course was more favorable for pure depression (n=267, median episode duration=6months, 24.5% chronic) than for pure anxiety (n=487, median duration=16months, 41.9% chronic). Worst course was observed in the comorbid depression–anxiety group (n=455, median duration >24months, 56.8% chronic …
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BWJH Penninx, WA Nolen, F Lamers, FG Zitman… - Journal of affective disorders, 2011