作者
Emmy Verheij, Laura SM Derks, Inge Stegeman, Hans GXM Thomeer
发表日期
2017/12
来源
Clinical otolaryngology
卷号
42
期号
6
页码范围
1319-1328
简介
Background
Hearing loss and otitis media are frequently reported in patients with 22q11.2 deletion syndrome.
Objective of review
Our objective was to review the current literature on the prevalence of hearing loss and otologic manifestations in patients with 22q11.2 deletion syndrome.
Type of review
Systematic review.
Search strategy
We conducted a systematic search in PubMed and Embase combining the term “22q11.2 deletion syndrome” and synonyms with “hearing loss” and “otologic manifestations” and synonyms.
Evaluation method
We screened title/abstract and full text of all retrieved articles on pre‐defined in‐ and exclusion criteria. The remaining articles were assessed on risk of bias. Outcome measures included the prevalence of hearing loss and otologic manifestations such as otitis media.
Results
Our search yielded 558 unique studies of which a total of 25 articles were included for critical …
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