发明者
Angela Nicole Koehler, Shelby Doyle, Becky Leifer, Madeleine Henley, Beat W Schaefer, Marco Wachtel
发表日期
2024/4/23
专利局
US
专利号
11964022
专利申请号
17946898
简介
The present disclosure provides compounds having the general formula PLU, or pharmaceutically acceptable salts thereof, wherein P is a FOXO1 fusion protein binding moiety, L is a bivalent linker, and U is an ubiquitin ligase binding moiety. Also provided are pharmaceutical compositions containing such compounds and methods of using such compounds.
学术搜索中的文章
AN Koehler, S Doyle, B Leifer, M Henley, BW Schaefer… - US Patent 11,964,022, 2024