作者
Manfred Kayser, Alessandra Caglia, DAniel Corach, Neale Fretwell, CHRISTIAN Gehrig, GIORGIO Graziosi, FRANK Heidorn, S Herrmann, BERGEN Herzog, MONIKA Hidding, KATSUYA Honda, M Jobling, MICHAEL Krawczak, KEIN Leim, SUSANNE Meuser, ECKHARD Meyer, WOLFGANG Oesterreich, ARPITA Pandya, W Parson, G Penacino, A Perez-Lezaun, ANDREA Piccinini, M Prinz, CORNELIA Schmitt, PETER M Schneider, REINHARD Szibor, JOHANNA Teifel-Greding, G Weichhold, PETER de Knijff, LUTZ Roewer
发表日期
1997/6
期刊
International journal of legal medicine
卷号
110
页码范围
125-133
出版商
Springer-Verlag
简介
A multicenter study has been carried out to characterize 13 polymorphic short tandem repeat (STR) systems located on the male specific part of the human Y chromosome (DYS19, DYS288, DYS385, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, YCAI, YCAII, YCAIII, DXYS156Y). Amplification parameters and electrophoresis protocols including multiplex approaches were compiled. The typing of non-recombining Y loci with uniparental inheritance requires special attention to population substructuring due to prevalent male lineages. To assess the extent of these subheterogeneities up to 3825 unrelated males were typed in up to 48 population samples for the respective loci. A consistent repeat based nomenclature for most of the loci has been introduced. Moreover we have estimated the average mutation rate for DYS19 in 626 confirmed father-son pairs as 3.2 × 10–3 (95% confidence interval …
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M Kayser, A Caglia, DA Corach, N Fretwell, C Gehrig… - International journal of legal medicine, 1997
