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Mobility and spatial interaction data have become increasingly available due to the wide adoption of location‐aware technologies. Examples of mobility data include human daily activities, vehicle trajectories, and animal movements, among others. In this article we focus on a special type of mobility data, i.e. origin‐destination pairs, and present a new approach to the discovery and understanding of spatio‐temporal patterns in the movements. Specifically, to extract information from complex connections among a large number of point locations, the approach involves two steps: (1) spatial clustering of massive GPS points to recognize potentially meaningful places; and (2) extraction and mapping of the flow measures of clusters to understand the spatial distribution and temporal trends of movements. We present a case study with a large dataset of taxi trajectories in Shenzhen, China to demonstrate and evaluate the …