作者
Adriano Mollica, Azzurra Stefanucci, Gokhan Zengin, Marcello Locatelli, Giorgia Macedonio, Giustino Orlando, Claudio Ferrante, Luigi Menghini, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Lidia Leporini, Chiara Di Nisio, Luigi Brunetti, Eltayeb Tayrab, Islam Ali, Taha H Musa, Hassan H Musa, Abdelkareem A Ahmed
发表日期
2018/11/1
期刊
Biomedicine & Pharmacotherapy
卷号
107
页码范围
129-138
出版商
Elsevier Masson
简介
In this study, three different extracts (soxhlet, microwave and decoction) from two species of broccoli: Brassica oleracea L. convar. Italica botrytis (L.) Alef. var. cymosa Duch. (Broccolo Fiolaro) and Brassica oleracea acephala L. convar. acephala (DC.) Alef. var. sabellica L. (Cavolo Nero), which are commonly spread in north-central Italy, were tested for their enzyme inhibitory effects. Enzyme inhibitory effects were investigated against cholinesterases, tyrosinase, α-amylase and α-glucosidase. The soxhlet extracts had the highest inhibitory AChE effects with 1.08 mgGALAE/g (in Cavolo Nero) and 0.90 mgGALAE/g (in Broccolo Fiolaro). The significant tyrosinase inhibitory effect was observed in the soxhlet extract of Cavolo Nero with 11.93 mgKAE/g. In addition, we evaluated the antioxidant activity of Broccolo Fiolaro and Cavolo Nero on lipopolysaccharide (LPS)-stimulated bladder, kidney and liver specimens, ex vivo …
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A Mollica, A Stefanucci, G Zengin, M Locatelli… - Biomedicine & Pharmacotherapy, 2018