作者
Seyed Mojtaba Sohrevardi, Fatemeh Shojaei Nasab, Mohammad Reza Mirjalili, Mohammad Bagherniya, Arefeh Dehghani Tafti, Mohammad Hossein Jarrahzadeh, Mahmoud Reza Azarpazhooh, Mohsen Saeidmanesh, Maciej Banach, Tannaz Jamialahmadi, Amirhossein Sahebkar
发表日期
2021
期刊
Archives of medical science: AMS
卷号
17
期号
5
页码范围
1423
出版商
Termedia Publishing
简介
Methods
In this randomized, double-blind and controlled trial, a total of 90 patients in the general ICU who had delirium for at least 2 days were randomly divided into atorvastatin (40 mg/day)(n= 40) and control (n= 50) groups. Delirium status of the patients was determined twice a day at 10: 00 am and 18: 00 pm using the Richmond Agitation-Sedation Scale (RASS).
Results
Administration 40 mg/day of atorvastatin significantly reduced the mean RASS score and increased delirium-free days at both morning and afternoon time points compared to the control group (p< 0.05).
Conclusions
Administration of atorvastatin had a significant positive effect on delirium status in patients admitted to the ICU.
学术搜索中的文章
SM Sohrevardi, FS Nasab, MR Mirjalili, M Bagherniya… - Archives of medical science: AMS, 2021