作者
Deborah A Theodore, Angela R Branche, Lily Zhang, Daniel S Graciaa, Madhu Choudhary, Timothy J Hatlen, Raadhiya Osman, Tara M Babu, Samuel T Robinson, Peter B Gilbert, Dean Follmann, Holly Janes, James G Kublin, Lindsey R Baden, Paul Goepfert, Glenda E Gray, Beatriz Grinsztejn, Karen L Kotloff, Cynthia L Gay, Brett Leav, Jacqueline Miller, Ian Hirsch, Jerald Sadoff, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Ann R Falsey, Hana M El Sahly, Magdalena E Sobieszczyk, Yunda Huang, Atoya Adams, Eric Miller, Bruce G Rankin, Steven Shinn, Marshall Nash, Sinikka L Green, Colleen Jacobsen, Jayasree Krishnankutty, Sikhongi Phungwayo, Richard M Glover, Stacy Slechta, Troy Holdeman, Robyn Hartvickson, Amber Grant, Terry L Poling, Terry D Klein, Thomas C Klein, Tracy R Klein, William B Smith, Richard L Gibson, Jennifer Winbigler, Elizabeth Parker, Priyantha N Wijewardane, Eric Bravo, Jeffrey Thessing, Michelle Maxwell, Amanda Horn, Catherine Mary Healy, Christine Akamine, Laurence Chu, R Michelle Chouteau, Michael J Cotugno, George H Bauer, Greg Hachigian, Masaru Oshita, Michael Cancilla, Kristen Kiersey, William Seger, Mohammed Antwi, Allison Green, Anthony Kim, Michael Desjardins, Jennifer A Johnson, Amy Sherman, Stephen R Walsh, Judith Borger, Nafisa Saleem, Joel Solis, Martha Carmen Medina, Westly Keating, Edgar Garcia, Cynthia Bueno, Nathan Segall, Douglas S Denham, Thomas Weiss, Ayoade Avworo, Parke Hedges, Cynthia Becher Strout, Rica Santiago, Yvonne Davis, Patty Howenstine, Alison Bondell, Kristin Marks, Tina Wang, Timothy Wilkin, Mary Vogler, Carrie Johnston, Michele P Andrasik, Jessica G Andriesen, Gail Broder, Niles Eaton, Huub G Gelderblom, Rachael McClennen, Nelson Michael, Merlin Robb, Carrie Sopher, Vicki E Miller, Fredric Santiago, Blanca Gomez, Insiya Valika, Amy Starr, Valeria D Cantos, Sheetal Kandiah, Carlos del Rio, Nadine Rouphael, Srilatha Edupuganti, Evan J Anderson, Andres Camacho-Gonzalez, Satoshi Kamidani, Christiana A Rostad, Meghan Teherani, David J Diemert, Elissa Malkin, Marc Siegel, Afsoon Roberts, Gary Simon, Bindu Balani, Carolene Stephenson, Steven Sperber, Cristina Cicogna, Marcus J Zervos, Paul Kilgore, Mayur Ramesh, Erica Herc, Kate Zenlea, Abram Burgher, Ann M Milliken, Joseph D Davis, Brendan Levy, Sandra Kelman, Matthew W Doust, Denise Sample, Sandra Erickson, Shane G Christensen, Christopher Matich, James Longe, John Witbeck, James T Peterson, Alexander Clark, Gerald Kelty
发表日期
2023/7/3
期刊
JAMA network open
卷号
6
期号
7
页码范围
e2323349-e2323349
出版商
American Medical Association
简介
Importance
Current data identifying COVID-19 risk factors lack standardized outcomes and insufficiently control for confounders.
Objective
To identify risk factors associated with COVID-19, severe COVID-19, and SARS-CoV-2 infection.
Design, Setting, and Participants
This secondary cross-protocol analysis included 4 multicenter, international, randomized, blinded, placebo-controlled, COVID-19 vaccine efficacy trials with harmonized protocols established by the COVID-19 Prevention Network. Individual-level data from participants randomized to receive placebo within each trial were combined and analyzed. Enrollment began July 2020 and the last data cutoff was in July 2021. Participants included adults in stable health, at risk for SARS-CoV-2, and assigned to the placebo group within each vaccine trial. Data were analyzed from April 2022 to February 2023.
Exposures
Comorbid conditions, demographic factors …
学术搜索中的文章
DA Theodore, AR Branche, L Zhang, DS Graciaa… - JAMA network open, 2023