作者
Sudipto Datta, Ripon Sarkar, Veena Vyas, Sumant Bhutoria, Ananya Barui, Amit Roy Chowdhury, Pallab Datta
发表日期
2018/7
期刊
Journal of Materials Research
卷号
33
期号
14
页码范围
2029-2039
出版商
Cambridge University Press
简介
The polysaccharide alginate has received most extensive attention as bioink in bioprinting applications due to its ability to undergo gelation under cell-friendly conditions. However, absence of cell-binding motifs and the erratic degradation of alginate hydrogels have remained their persistent limitations. Honey is a conveniently available natural material, known for its role in wound healing and skin tissue regeneration. However, honey blending to improve biological response of alginate-based bioprinted scaffolds has not been yet reported. In the present work, honey-alginate bioinks were evaluated for their printability property (shape fidelity). It was found that honey blending reduced alginate viscosity, which gradually affected bioprinting fidelity. Therefore, the concentration that provides for acceptable bioprinting along with improvement in cell proliferations is determined. It is concluded that honey blending improves …
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S Datta, R Sarkar, V Vyas, S Bhutoria, A Barui… - Journal of Materials Research, 2018