作者
Ripon Sarkar, Aritri Ghosh, Ananya Barui, Pallab Datta
发表日期
2018/3
期刊
Journal of Materials Science: Materials in Medicine
卷号
29
页码范围
1-16
出版商
Springer US
简介
Topical application of honey for tissue regeneration, has recently regained attention in clinical practice with controlled studies affirming its efficacy and indicating its role in regeneration over repair. Parallely, to overcome difficulties of applying raw honey, several product development studies like nanofibrous matrices have been reported. However, one approach concentrated on achieving highest possible honey loading in the nanofiber membranes while other studies have found that only specific honey dilutions result in differential cellular responses on wound healing and re-epithelization. From these results, it can be suggested that high honey loading provides optimum external microenvironment, low-loaded membranes could provide a more conducive internal microenvironment for tissue regeneration. With this hypothesis, this paper sought to evaluate ability of low-honey loaded nanofibers to modulate …
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R Sarkar, A Ghosh, A Barui, P Datta - Journal of Materials Science: Materials in Medicine, 2018