作者
Nick A Weaver, Angelina K Kancheva, Jae-Sung Lim, J Matthijs Biesbroek, Irene MC Huenges Wajer, Yeonwook Kang, Beom J Kim, Hugo J Kuijf, Byung-Chul Lee, Keon-Joo Lee, Kyung-Ho Yu, Geert Jan Biessels, Hee-Joon Bae
发表日期
2021/10
期刊
International Journal of Stroke
卷号
16
期号
8
页码范围
981-989
出版商
SAGE Publications
简介
Background
Post-stroke cognitive impairment can occur after damage to various brain regions, and cognitive deficits depend on infarct location. The Mini-Mental State Examination (MMSE) is still widely used to assess post-stroke cognition, but it has been criticized for capturing only certain cognitive deficits. Along these lines, it might be hypothesized that cognitive deficits as measured with the MMSE primarily involve certain infarct locations.
Aims
This comprehensive lesion-symptom mapping study aimed to determine which acute infarct locations are associated with post-stroke cognitive impairment on the MMSE.
Methods
We examined associations between impairment on the MMSE (<5th percentile; normative data) and infarct location in 1198 patients (age 67 ± 12 years, 43% female) with acute ischemic stroke using voxel-based lesion-symptom mapping. As a frame of reference, infarct patterns associated with …
学术搜索中的文章
NA Weaver, AK Kancheva, JS Lim, JM Biesbroek… - International Journal of Stroke, 2021
