作者
Mina A Jacob, Merel S Ekker, Youssra Allach, Mengfei Cai, Karoliina Aarnio, Antonio Arauz, Marcel Arnold, Hee-Joon Bae, Lucrecia Bandeo, Miguel A Barboza, Manuel Bolognese, Pablo Bonardo, Raf Brouns, Batnairamdal Chuluun, Enkhzaya Chuluunbatar, Charlotte Cordonnier, Byambasuren Dagvajantsan, Stephanie Debette, Adi Don, Chris Enzinger, Esme Ekizoglu, Simon Fandler-Höfler, Franz Fazekas, Annette Fromm, Thomas Gattringer, Thiago F Hora, Christina Jern, Katarina Jood, Young Seo Kim, Steven Kittner, Timothy Kleinig, Catharina JM Klijn, Janika Korv, Vinod Kumar, Keon-Joo Lee, Tsong-Hai Lee, Noortje AM Maaijwee, Nicolas Martinez-Majander, João Pedro Marto, Man M Mehndiratta, Victoria Mifsud, Vinícius Montanaro, Gisele Pacio, Vinod B Patel, Matthew C Phillips, Bartlomiej Piechowski-Jozwiak, Aleksandra Pikula, Jose Ruiz-Sandoval, Bettina Von Sarnowski, Richard H Swartz, Kay-Sin Tan, David Tanne, Turgut Tatlisumak, Vincent Thijs, Miguel Viana-Baptista, Riina Vibo, Teddy Y Wu, Nilüfer Yesilot, Ulrike Waje-Andreassen, Alessandro Pezzini, Jukka Putaala, Anil M Tuladhar, Frank-Erik de Leeuw
发表日期
2022/2/8
期刊
Neurology
卷号
98
期号
6
页码范围
e573-e588
出版商
Lippincott Williams & Wilkins
简介
Background and Objectives
There is a worldwide increase in the incidence of stroke in young adults, with major regional and ethnic differences. Advancing knowledge of ethnic and regional variation in causes and outcomes will be beneficial in implementation of regional health care services. We studied the global distribution of risk factors, causes, and 3-month mortality of young patients with ischemic stroke, by performing a patient data meta-analysis from different cohorts worldwide.
Methods
We performed a pooled analysis of individual patient data from cohort studies that included consecutive patients with ischemic stroke aged 18–50 years. We studied differences in prevalence of risk factors and causes of ischemic stroke between different ethnic and racial groups, geographic regions, and countries with different income levels. We investigated differences in 3-month mortality by mixed-effects multivariable logistic …
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