作者
M Zibetti, E Torre, A Cinquepalmi, M Rosso, Alessandro Ducati, Bruno Bergamasco, M Lanotte, Leonardo Lopiano
发表日期
2007/11/1
期刊
European neurology
卷号
58
期号
4
页码范围
218-223
出版商
S. Karger AG
简介
Objective
To evaluate motor and nonmotor symptoms in patients with Parkinson’s disease undergoing bilateral deep brain stimulation of the subthalamic nucleus (STN DBS).
Methods
Thirty-six consecutive patients receiving bilateral STN stimulation implants were evaluated preoperatively as well as 12 and 24 months after surgery. Motor symptoms were assessed through the Unified Parkinson’s Disease Rating Scale (UPDRS). Data concerning nonmotor symptoms were collected from items of the UPDRS and 2 additional questions from clinical charts regarding constipation and urological dysfunction.
Results
STN DBS was effective in controlling motor symptoms; concerning nonmotor symptoms, sleep quality and constipation improved after surgery as compared to baseline. Salivation, swallowing and sensory complaints were ameliorated to a comparable degree by the medication on state, whether preoperatively …
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