查看文章

Purpose:

To perform advanced analysis of the corneal deformation response to air pressure in keratoconics compared with age-and sex-matched controls.

Methods:

The ocular response analyzer was used to measure the air pressure–corneal deformation relationship of 37 patients with keratoconus and 37 age (mean 36±10 years)-and sex-matched controls with healthy corneas. Four repeat air pressure–corneal deformation profiles were averaged, and 42 separate parameters relating to each element of the profiles were extracted. Corneal topography and pachymetry were performed with the Orbscan II. The severity of the keratoconus was graded based on a single metric derived from anterior corneal curvatures, difference in astigmatism in each meridian, anterior best-fit sphere, and posterior best-fit sphere.

Results:

Most of the biomechanical characteristics of keratoconic eyes were significantly different from normal …