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Study Design.

Prospective clinical study.

Objective.

To assess Health-Related Quality of Life outcomes in patients undergoing surgery for spinal metastases.

Summary of Background Data.

Increasing life expectancy of patients with spinal metastases has resulted in greater interest in overall quality of life, including pain and neurologic impairment. To assess the overall risks and benefits of surgical intervention, the overall impact of each on the overall health status must be assessed.

Methods.

All patients who presented to a single institution with bony spinal metastases requiring surgical intervention were eligible. Exclusion criteria: previous surgery for spinal metastases, primary tumors of the spine, and inability to fill out the questionnaires. Patients completed an EORTC QLQ-C30, the HUI-3, the EQ-5D, visual analog pain, and an ECOG functional assessment. at five points: before surgery and at 6 weeks, 3 months, 6 …