作者
Lorenzo Bianchi, Paolo Castellucci, Andrea Farolfi, Matteo Droghetti, Carlos Artigas, Jose Leite, Paola Corona, Qaid Ahmed Shagera, Renata Moreira, Christian González, Marcelo Queiroz, Felipe de Galiza Barbosa, Riccardo Schiavina, Desiree Deandreis, Stefano Fanti, Francesco Ceci
发表日期
2023/2/1
期刊
European Urology Oncology
卷号
6
期号
1
页码范围
41-48
出版商
Elsevier
简介
Background
A nomogram has recently been developed to predict 68Ga-labeled prostate-specific membrane antigen (PSMA)-11 positron emission tomography (PET)/computed tomography (PSMA-PET) results in recurrent prostate cancer (PCa) patients.
Objective
To perform external validation of the original nomogram in a multicentric setting.
Design, setting, and participants
A total of 1639 patients who underwent PSMA-PET for prostate-specific antigen (PSA) relapse after radical therapy were retrospectively included from six high-volume PET centers. The external cohort was stratified according to clinical setting categories: group 1: first-time biochemical recurrence (n = 774); group 2: PSA relapse after salvage therapy (n = 499); group-3: biochemical persistence after radical prostatectomy (n = 210); and group-4: advanced-stage PCa before second-line systemic therapies (n = 124).
Intervention
PSMA-PET in recurrent …
学术搜索中的文章
L Bianchi, P Castellucci, A Farolfi, M Droghetti… - European Urology Oncology, 2023