作者
Lindsay M Morton, Susan L Slager, James R Cerhan, Sophia S Wang, Claire M Vajdic, Christine F Skibola, Paige M Bracci, Silvia de Sanjosé, Karin E Smedby, Brian CH Chiu, Yawei Zhang, Sam M Mbulaiteye, Alain Monnereau, Jennifer J Turner, Jacqueline Clavel, Hans-Olov Adami, Ellen T Chang, Bengt Glimelius, Henrik Hjalgrim, Mads Melbye, Paolo Crosignani, Simonetta di Lollo, Lucia Miligi, Oriana Nanni, Valerio Ramazzotti, Stefania Rodella, Adele Seniori Costantini, Emanuele Stagnaro, Rosario Tumino, Carla Vindigni, Paolo Vineis, Nikolaus Becker, Yolanda Benavente, Paolo Boffetta, Paul Brennan, Pierluigi Cocco, Lenka Foretova, Marc Maynadié, Alexandra Nieters, Anthony Staines, Joanne S Colt, Wendy Cozen, Scott Davis, Anneclaire J de Roos, Patricia Hartge, Nathaniel Rothman, Richard K Severson, Elizabeth A Holly, Timothy G Call, Andrew L Feldman, Thomas M Habermann, Mark Liebow, Aaron Blair, Kenneth P Cantor, Eleanor V Kane, Tracy Lightfoot, Eve Roman, Alex Smith, Angela Brooks-Wilson, Joseph M Connors, Randy D Gascoyne, John J Spinelli, Bruce K Armstrong, Anne Kricker, Theodore R Holford, Qing Lan, Tongzhang Zheng, Laurent Orsi, Luigino Dal Maso, Silvia Franceschi, Carlo La Vecchia, Eva Negri, Diego Serraino, Leslie Bernstein, Alexandra Levine, Jonathan W Friedberg, Jennifer L Kelly, Sonja I Berndt, Brenda M Birmann, Christina A Clarke, Christopher R Flowers, James M Foran, Marshall E Kadin, Ora Paltiel, Dennis D Weisenburger, Martha S Linet, Joshua N Sampson
发表日期
2014/8/1
期刊
Journal of the National Cancer Institute Monographs
卷号
2014
期号
48
页码范围
130-144
出版商
Oxford University Press
简介
Background
Non-Hodgkin lymphoma (NHL) comprises biologically and clinically heterogeneous subtypes. Previously, study size has limited the ability to compare and contrast the risk factor profiles among these heterogeneous subtypes.
Methods
We pooled individual-level data from 17 471 NHL cases and 23 096 controls in 20 case–control studies from the International Lymphoma Epidemiology Consortium (InterLymph). We estimated the associations, measured as odds ratios, between each of 11 NHL subtypes and self-reported medical history, family history of hematologic malignancy, lifestyle factors, and occupation. We then assessed the heterogeneity of associations by evaluating the variability (Q value) of the estimated odds ratios for a given exposure among subtypes. Finally, we organized the subtypes into a hierarchical tree to identify groups that had similar risk …
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