作者
E Ann Yeh, Emmanuelle Waubant, Lauren B Krupp, Jayne Ness, Tanuja Chitnis, Nancy Kuntz, Murali Ramanathan, Anita Belman, Dorothee Chabas, Mark P Gorman, Moses Rodriguez, John Robert Rinker, Bianca Weinstock-Guttman
发表日期
2011/4/11
期刊
Archives of neurology
卷号
68
期号
4
页码范围
437-444
出版商
American Medical Association
简介
Background: Currently available disease-modifying therapies (DMTs) are known to be only partially effective in adults with multiple sclerosis (MS). Little is known about pediatric patients with MS who experience refractory disease while receiving first-line DMTs.
Objective: To assess the occurrence and management of refractory disease in a group of pediatric patients with MS treated with first-line DMTs approved for adult patients within a network of pediatric MS centers in the United States.
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