作者
Madhura Ingalhalikar, Alex Smith, Drew Parker, Theodore D Satterthwaite, Mark A Elliott, Kosha Ruparel, Hakon Hakonarson, Raquel E Gur, Ruben C Gur, Ragini Verma
发表日期
2014/1/14
期刊
Proceedings of the National Academy of Sciences
卷号
111
期号
2
页码范围
823-828
出版商
National Academy of Sciences
简介
Sex differences in human behavior show adaptive complementarity: Males have better motor and spatial abilities, whereas females have superior memory and social cognition skills. Studies also show sex differences in human brains but do not explain this complementarity. In this work, we modeled the structural connectome using diffusion tensor imaging in a sample of 949 youths (aged 8–22 y, 428 males and 521 females) and discovered unique sex differences in brain connectivity during the course of development. Connection-wise statistical analysis, as well as analysis of regional and global network measures, presented a comprehensive description of network characteristics. In all supratentorial regions, males had greater within-hemispheric connectivity, as well as enhanced modularity and transitivity, whereas between-hemispheric connectivity and cross-module participation predominated in females …
引用总数
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