作者
Daniel C Beachler, Kathleen M Weber, Joseph B Margolick, Howard D Strickler, Ross D Cranston, Robert D Burk, Dorothy J Wiley, Howard Minkoff, Susheel Reddy, Emily E Stammer, Maura L Gillison, Gypsyamber D'Souza
发表日期
2012/1/1
期刊
Cancer Epidemiology, Biomarkers & Prevention
卷号
21
期号
1
页码范围
122-133
出版商
American Association for Cancer Research
简介
Introduction: Human papillomavirus (HPV) is an important risk factor for oropharyngeal cancer. Individuals with human immunodeficiency virus (HIV) have higher oral HPV prevalence but the risk factors for oral HPV infection are not well understood for either HIV-positive or HIV-negative individuals.
Methods: This study was nested within the Multicenter AIDS Cohort Study (MACS; men) and Women Interagency HIV Study (WIHS; women) cohorts. Exfoliated oral epithelial cells were collected from 379 HIV-positive and 266 at-risk HIV-negative individuals using a rinse and gargle with Scope mouthwash. Samples were tested for 36 types of HPV DNA using PGMY09/11 consensus primers and reverse line blot hybridization. Risk factors for oral HPV infection were explored using logistic regression with generalized estimating equations in this cross-sectional analysis.
Results: Prevalent …
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DC Beachler, KM Weber, JB Margolick, HD Strickler… - Cancer Epidemiology, Biomarkers & Prevention, 2012