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Lipases belong to a class of triacylglycerol hydrolases possessing a lot of potential applications due to their various physical properties. Most of the lipase producers are extracellular in nature are produced using solid-state fermentation and submerged fermentation methods. The fungal, mycelial, and the yeast lipases are produced using various solid substrates through solid-state fermentation method. This method is cost effective and hence widely used in industries to produce lipase using fungi. Whereas lipases from bacteria, were produced using submerged fermentation. The optimization of media is a main requirement for increasing the quantitative yield by overproduction of enzymes. The optimization of media is a main requirement for increasing the quantitative yield by overproduction of enzymes. Different parameters such as pH, temperature, agitation speed, inoculum size, incubation time, carbon and …