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Deductive formalisms have been strongly developed in recent years; among them, answer set programming (ASP) gained some momentum and has been lately fruitfully employed in many real-world scenarios. Nonetheless, in spite of a large number of success stories in relevant application areas, and even in industrial contexts, deductive reasoning cannot be considered the ultimate, comprehensive solution to artificial intelligence; indeed, in several contexts, other approaches result to be more useful. Typical bioinformatics tasks, for instance classification, are currently carried out mostly by machine learning (ML)-based solutions. In this paper, we focus on the relatively new problem of analyzing the evolution of neurological disorders. In this context, ML approaches already demonstrated to be a viable solution for classification tasks; here, we show how ASP can play a relevant role in the brain evolution simulation …