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Objective:

Hypertension is often associated with coronary heart disease and coronary artery bypass surgery usually performed in this condition. Currently, there are no studies evaluating the anti-inflammatory effect of captopril in hypertensive patients who undergo coronary artery bypass surgery.

Design and method:

We conducted a prospective observational study on 45 subjects with hypertension who underwent coronary artery bypass surgery. Levels of inflammation examined by high sensitive c-reactive protein. High sensitive c-reactive protein was measured three times (day prior surgery, third and sixth day after surgery).

Results:

Total sample population were 45 subjects with hypertension before and after coronary artery bypass surgery, consisting of 18 subjects did not received captopril and 27 subjects received captopril. There were no significant differences in the factors affecting the increased of high sensitive …