作者
Carolyn SP Lam, Tiew-Hwa Katherine Teng, Wan Ting Tay, Inder Anand, Shu Zhang, Wataru Shimizu, Calambur Narasimhan, Sang Weon Park, Cheuk-Man Yu, Tachapong Ngarmukos, Razali Omar, Eugene B Reyes, Bambang B Siswanto, Chung-Lieh Hung, Lieng H Ling, Jonathan Yap, Michael MacDonald, A Mark Richards
发表日期
2016/11/1
期刊
European heart journal
卷号
37
期号
41
页码范围
3141-3153
出版商
Oxford University Press
简介
Aims
To characterize regional and ethnic differences in heart failure (HF) across Asia.
Methods and results
We prospectively studied 5276 patients with stable HF and reduced ejection fraction (≤40%) from 11 Asian regions (China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Philippines, Singapore, Taiwan, and Thailand). Mean age was 59.6 ± 13.1 years, 78.2% were men, and mean body mass index was 24.9 ± 5.1 kg/m2. Majority (64%) of patients had two or more comorbid conditions such as hypertension (51.9%), coronary artery disease (CAD, 50.2%), or diabetes (40.4%). The prevalence of CAD was highest in Southeast Asians (58.8 vs. 38.2% in Northeast Asians). Compared with Chinese ethnicity, Malays (adjusted odds ratio [OR] 1.97, 95% CI 1.63–2.38) and Indians (OR 1.44, 95% CI 1.24–1.68) had higher odds of CAD, whereas Koreans (OR 0.38, 95% CI 0.29–0 …
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