作者
Raef Ali Fadel, Renato Cerna Viacava, Tarek Makki, Carina Dagher Fadel, Kelly Malette, Zachary D Demertzis, Guneet Ahluwalia, Joseph Miller, Cori Russell
发表日期
2023/8/1
期刊
Heliyon
卷号
9
期号
8
出版商
Elsevier
简介
Background
Guidelines recommend targeting decongestion in management of decompensated HF, with lower extremity edema often serving as the clinical target. LECW are seldom used in the acute setting, with a paucity of data on efficacy in HF, despite serving as a cornerstone of chronic lymphedema management.
Primary objective
Study the efficacy and safety of LECW in acute decompensated HF.
Methods
Open-label, randomized, parallel-group clinical trial.
Primary outcomes
Days on intravenous (IV) diuretic therapy, total hospital length of stay (LOS), and 30-day all-cause readmission.
Results
32 patients were enrolled, with 29 patients completing the study. Enrollment was suspended due to the COVID-19 pandemic. Overall LOS was shorter in the intervention group (3.5 vs 6 days, p = 0.05), with no significant difference in total days on IV diuresis or 30-day readmission rate with use of LECW. Fewer patients …
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RA Fadel, RC Viacava, T Makki, CD Fadel, K Malette… - Heliyon, 2023