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Recently emerged electronic skins with applications in on-body sensing and human–machine interfaces call for the development of high-performance skin-like electrodes. In this work, we report a highly robust, transparent, and breathable epidermal electrode composed of a scaffold-reinforced conductive nanonetwork (SRCN). Solution-dispersed Ag nanowires, through facile vacuum filtration, are embedded into a scaffold made of polyamide nanofibers. Optical transmittance of 84.9% at 550 nm wavelength is achieved at a significantly low sheet resistance of 8.2 Ω sq^–1. The resistance of the SRCN only slightly increases by less than 0.1% after being bent for 3000 cycles at the maximum curvature of 300 m^–1 and by less than 1.5% after being dipped in saline solution for 2500 cycles. The excellent robustness is attributed to the reinforcement from the nanofiber-based scaffold as a backbone that maintains the …