作者
JG Mainil, Georges Daube
发表日期
2005/6/1
来源
Journal of Applied Microbiology
卷号
98
期号
6
页码范围
1332-1344
出版商
Blackwell Science Ltd
简介
Verocytotoxigenic (shigatoxigenic) and enterohaemorrhagic Escherichia coli, VTEC (STEC) and EHEC, produce a toxin active on Vero cells in vitro. VTEC and EHEC have been isolated from humans and different animal species, mainly ruminants and pigs. The verocytotoxins, also named shiga toxins (Stx), are active in vivo on the endothelial cells of the blood vessels of the gastro‐intestinal mucosa, the kidneys, the brain, and other tissues of humans and piglets, leading to fluid leakage or haemorrhages. Conversely, their role in diseases of young ruminants remains unclear. Adult ruminants can also act as asymptomatic carriers of VTEC and EHEC strains similar to those causing diseases in humans. And they are incriminated as an important source of direct or indirect contamination of humans by the most famous EHEC strain belonging to the O157: H7 serotype, through faecal contamination of either foods of …
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