作者
Amir Ghaderi, Omid Asbaghi, Željko Reiner, Fariba Kolahdooz, Elaheh Amirani, Hamed Mirzaei, Hamid Reza Banafshe, Parisa Maleki Dana, Zatollah Asemi
发表日期
2020/1/1
来源
Complementary therapies in medicine
卷号
48
页码范围
102250
出版商
Churchill Livingstone
简介
Background
The findings of trials investigating the effects of saffron (Crocus sativus L.) supplementation on depression, anxiety, and C-reactive protein (CRP) are inconsistent. The current meta-analysis of randomized controlled trials (RCTs) was carried out to assess the effects of saffron (Crocus sativus L.) administration on mental health parameters and CRP levels.
Methods
Two independent authors systematically searched online databases including EMBASE, Scopus, PubMed, Cochrane Library, and Web of Science from inception until 30th July 2019. Cochrane Collaboration risk of bias tool was applied to assess the methodological quality of included trials. The heterogeneity among the included studies was assessed using Cochrane’s Q test and I-square (I2) statistic. Data were pooled using a random-effects model and weighted mean difference (WMD) was considered as the overall effect size.
Results
Twenty …
引用总数
20202021202220232024781384
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A Ghaderi, O Asbaghi, Ž Reiner, F Kolahdooz… - Complementary therapies in medicine, 2020