作者
Rakesh Tamang, Gyaneshwer Chaubey, Amrita Nandan, Periyasamy Govindaraj, Vipin Kumar Singh, Niraj Rai, Chandana Basu Mallick, Vishwas Sharma, Varun Kumar Sharma, Anish M Shah, Albert Lalremruata, Alla G Reddy, Deepa Selvi Rani, Pilot Doviah, Neetu Negi, Yarin Hadid, Veena Pande, Satti Vishnupriya, George Van Driem, Doron M Behar, Tikaram Sharma, Lalji Singh, Richard Villems, Kumarasamy Thangaraj
发表日期
2018/2
期刊
Human genetics
卷号
137
页码范围
129-139
出版商
Springer Berlin Heidelberg
简介
The rugged topography of the Himalayan region has hindered large-scale human migrations, population admixture and assimilation. Such complexity in geographical structure might have facilitated the existence of several small isolated communities in this region. We have genotyped about 850,000 autosomal markers among 35 individuals belonging to the four major populations inhabiting the Himalaya and adjoining regions. In addition, we have genotyped 794 individuals belonging to 16 ethnic groups from the same region, for uniparental (mitochondrial and Y chromosomal DNA) markers. Our results in the light of various statistical analyses suggest a closer link of the Himalayan and adjoining populations to East Asia than their immediate geographical neighbours in South Asia. Allele frequency-based analyses likely support the existence of a specific ancestry component in the Himalayan and adjoining …
引用总数
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